metabolism & bioenergetics

This study investigates brain-body interactions during food anticipation using multimodal physiological recordings, finding distinct changes in gastric and cortical responses linked to appetite and craving.

LuCEMe is a luciferase-based method to assess cellular metabolism in various systems, revealing metabolic differences in cancer and immune cell interactions.

The paper characterizes microbial communities and metabolic potential in northern palsa and peat ecosystems, finding distinct microbial profiles and highlighting hydrogen and carbon monoxide metabolism as key energy sources.

This study shows that older adults exhibit enhanced implicit motor adaptation only with consistent errors, not variable ones, suggesting error consistency is key for age-related adaptation.

This study investigates changes in carotid body mitochondrial function in heart failure, finding decreased oxygen affinity and increased oxidative stress.

This study shows ATF3 helps macrophages manage cholesterol during metabolic stress by balancing inflammation and sterol-responsive gene expression.

This paper uniformly re-analyzes public omics data from exercise studies in humans and rodents, providing standardized effect sizes and meta-analyses across multiple tissues and molecular layers.

The paper uses genome-scale modelling and stable isotope tracing to study metabolic changes in human cardiac hypertrophy models.

This study evaluates a M4-selective PAM in nonhuman primates, showing broad cognitive and motivational improvements without adverse side effects.

The paper shows neurons entrain an intrinsic arteriole rhythm, shaping blood distribution and vascular responses through frequency-dependent mechanisms.

This study identifies an internal chemosensory system in Drosophila melanogaster's abdomen using Gustatory Receptors, revealing new roles in interoception beyond traditional feeding behaviors.

This study examines proteomic changes in Geodermatophilus obscurus G20 under UV stress, showing distinct responses in acute and recovery phases.

This study examines the effects of isocaloric high-fat diet restriction with TAK-242 on metabolic and gut microbial responses in mice, finding limited normalization of adiposity and microbial community.

The paper identifies oleate depletion as a metabolic signal sensed by C. elegans to activate innate immunity against bacterial infection.

This study examines sex differences in muscle volume, strength, and motor unit properties during bed rest and retraining in young males and females, finding no sex differences in strength loss but greater MU firing rate reduction in females.

This study identifies Roseburia hominis-derived 10-hydroxystearic acid as a metabolite that improves metabolic health by restoring hepatic fatty acid metabolism in mice.

The paper constructs genome-scale metabolic models for soil bacteria to identify phylogenetically conserved fermentation traits and their metabolic fluxes.

This study engineers Saccharomyces cerevisiae to produce polyphosphate more efficiently by modifying metabolic pathways and growth conditions.

This study develops tetrasulfide-incorporated mesoporous silica nanoparticles to enhance mRNA delivery by optimizing morphology and chemistry, showing improved cellular uptake and mRNA stability.

The paper shows that CO2-concentrating nanoparticles modify photosynthesis and cell wall structure in Arabidopsis cells over time.

This study examines how antibiotics affect immune cell function by altering mitochondrial activity, showing antibiotic-specific immunomodulatory effects in humans and mice.

This study develops an LRH-1 agonist that improves insulin sensitivity and reduces liver fat in obese mice, revealing peroxisomal lipid metabolism as a key pathway.

This study uses biosensor-guided CRISPR screens in yeast to identify genetic targets that enhance production of cis,cis-muconic acid and protocatechuic acid.

This study investigates proteome changes in multiple organs of mice with Anorexia Nervosa using a gut microbiota-depleted model, identifying microbiota-dependent and -independent protein alterations.

The paper uses enzyme-constrained metabolic modeling to show that Picochlorum celeri's rapid growth at elevated CO2 is due to protein budget allocation, not enzyme abundance.

This study shows compost improves tomato drought resilience by enhancing water retention and modulating root gene expression through its microbial community.

The paper presents a multimodal dataset from a 40-hour forced-desynchrony protocol to study circadian rhythms and their effects on physiology, ocular function, and behavior.

The paper quantifies phloem conduit geometry and carbohydrate concentrations in avocado plants during development, showing changes in phloem structure and transport efficiency.

The paper shows that fatty acid desaturation, specifically DGLA, influences cellular decisions between ferroptosis and senescence, with implications for aging and obesity.

This paper uses Ensemble Kalman Filters to estimate intracellular nucleotide sugar donors in CHO cell cultures from extracellular measurements, improving metabolic state inference.