HypercubeME: two hundred million combinatorially complete datasets from a single experiment
L. Avino Esteban, L. R. Lonishin, D. Bobrovskiy, G. Leleytner, N. S. Bogatyreva, F. A. Kondrashov, D. N. Ivankov
The paper introduces an algorithm to identify combinatorially complete datasets in high-throughput mutagenesis experiments and applies it to find over 199 million such datasets in a HIS3 protein experiment.
bioRxiv · Aug 21, 2019Evolutionary Biology