Evolutionary BiologybioRxiv
HypercubeME: two hundred million combinatorially complete datasets from a single experiment
L. Avino Esteban, L. R. Lonishin, D. Bobrovskiy…·D. N. Ivankov
The paper introduces an algorithm to identify combinatorially complete datasets in high-throughput mutagenesis experiments and applies it to find over 199 million such datasets in a HIS3 protein experiment.
DOI 10.1093/bioinformatics/btz841