HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
N. Talledge, H. Yang, K. Shi, R. Coray, G. Yu, W. G. Arndt, S. Meng, G. C. Baxter, L. Mendonca, D. Castano-Dlez, H. Aihara, L. M. Mansky, W. Zhang
This study determines the 3D structure of HIV-2 immature Gag lattice using cryo-EM and identifies structural features critical for particle release and infectivity.
bioRxiv · Feb 1, 2022Microbiology