ImmunologybioRxiv
A bacterial microbiome is dispensable for the induction of CD8 T cell exhaustion
M. Kuhlmann, D. D. C. Kolland, G. P. d. Almeida…·D. Zehn
This study shows that the microbiome is not required for T cell exhaustion in chronic LCMV infections, as germ-free mice exhibit similar exhaustion markers and gene expression patterns to specific pathogen-free mice.
DOI 10.1002/eji.70238