MitoROS due to loss of Slc4a11 in corneal endothelial cells induces ER stress, lysosomal dysfunction and impairs autophagy
R. Shyam, D. G. Ogando, M. Choi, J. A. Bonanno
This study shows that loss of Slc4a11 in corneal endothelial cells leads to mitochondrial ROS, which causes ER stress, lysosomal dysfunction, and impaired autophagy.
bioRxiv · Aug 27, 2020Cell Biology