Defective ORF8 dimerization in delta variant of SARS CoV2 leads to abrogation of ORF8 MHC-I interaction and overcome suppression of adaptive immune response
A. Chaudhari, D. I. Singh, D. M. Joshi, D. A. PATEL, P. C. Joshi
The paper investigates how mutations in the ORF8 protein of the SARS-CoV-2 delta variant affect its dimerization and interaction with MHC-I, potentially reducing immune suppression.
bioRxiv · Aug 24, 2021 · PreprintBiophysics