Frataxin-deficient human brain microvascular endothelial cells lose polymerized actin and are paracellularly permeable -implications for blood-brain barrier integrity in Friedreich's Ataxia
This study shows that reduced frataxin in brain microvascular endothelial cells causes loss of actin and increased permeability, potentially contributing to neurological issues in Friedreich's Ataxia.
bioRxiv · Feb 9, 2023 · PreprintBiochemistry