"Multiplex" rheostat positions cluster around allosterically critical regions of the lactose repressor protein
L. E. Bantis, D. J. Parente, A. W. Fenton, L. Swint-Kruse
The paper identifies multiplex rheostat positions in LacI that modulate multiple functional parameters and shows they overlap with allosteric regions, suggesting complex biophysical effects.
bioRxiv · Nov 17, 2020 · PreprintBiochemistry