Author

T. A. Martin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. W. Fenton· 1 shared C. E. Fowler· 1 shared C. G. Mayne· 1 shared D. J. Hosfield· 1 shared D. J. Parente· 1 shared E. Tajkhorshid· 1 shared G. Buchwalter· 1 shared G. L. Greene· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. W. Fenton

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Author profile →

2 papers

Recent·Most cited

Identification of biochemically neutral positions in liver pyruvate kinase

T. A. Martin, T. Wu, Q. Tang, L. L. Dougherty, D. J. Parente, L. Swint-Kruse, A. W. Fenton

The paper identifies biochemically neutral positions in human liver pyruvate kinase by analyzing evolutionary patterns and functional outcomes of amino acid substitutions.

bioRxiv · May 12, 2020Biochemistry

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

S. W. Fanning, R. Jeselsohn, V. Dharmarajan, C. G. Mayne, M. Karimi, G. Buchwalter, R. Houtman, W. Toy, C. E. Fowler, M. Laine, K. E. Carlson, T. A. Martin, J. Nowak, J. C. Nwachukwu, D. J. Hosfield, , G. L. Greene

This study shows that bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells by inhibiting Y537S and D538G ER mutants more effectively than tamoxifen.

bioRxiv · Apr 23, 2018Cancer Biology