Developing a newborn rat model of meningitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli
W. S. Park, S. Y. AHN, Y. S. Chang, D. K. Sung, Y. E. Kim, S. I. Sung, S. Y. JOO
This study develops a newborn rat model of meningitis without systemic bacteremia using intraventricular injection of K1-negative E. coli, showing dose-dependent survival and brain injury.
bioRxiv · Aug 3, 2018Microbiology