Consequences of PDGFRα+ fibroblast reduction in adult murine hearts
J. T. Kuwabara, S. Bhutada, V. Shettigar, G. S. Gojanovich, L. P. DeAngelo, J. R. Heckl, J. R. Johansooz, D. K. Tacdol, M. T. Ziolo, S. S. Apte, M. D. Tallquist
This study shows that reducing PDGFRα+ fibroblasts in adult mice improves cardiac function after injury without altering fibrillar collagen, suggesting potential therapeutic benefits.
bioRxiv · May 7, 2021Cell Biology