Author

D. Krizanc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Organism:E. coli· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

K. Scopino· 3 shared M. P. Weir· 3 shared C. Dalgarno· 2 shared K. M. Thayer· 2 shared A. Elsayed· 1 shared A. Wang· 1 shared C. Nachmannoff· 1 shared C. Nachmanoff· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiophysics

K. Scopino

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Author profile →

4 papers

Recent·Most cited

The CAR mRNA-Interaction Surface is a Zipper Extension of the Ribosome A Site

C. Dalgarno, K. Scopino, M. Raval, C. Nachmanoff, E. Sakkas, D. Krizanc, K. Thayer, M. P. Weir

The paper investigates the CAR-mRNA interaction surface, revealing its sequence specificity and role in translational regulation through molecular dynamics and nucleotide substitution experiments.

bioRxiv · Jan 6, 2022Biophysics

Arginine Methylation Regulates Ribosome CAR Function

K. Scopino, C. Dalgarno, C. Nachmannoff, D. Krizanc, K. M. Thayer, M. P. Weir

This study shows that arginine methylation of ribosomal protein R146 reduces CAR interaction with the +1 codon, affecting translation regulation under stress.

bioRxiv · Dec 21, 2020Biophysics

A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity

K. Scopino, E. Williams, A. Elsayed, W. A. Barr, D. Krizanc, K. M. Thayer, M. P. Weir

The paper identifies a ribosome surface that interacts with mRNA GCN codons, showing sequence-specific hydrogen bonding that influences translation regulation.

bioRxiv · Apr 28, 2020Biophysics

Delving below the species level to characterize the ecological diversity within the global virome: An exploration of West Nile Virus

T. Kong, K. Mei, A. Wang, D. Krizanc, F. M. Cohan

The paper demonstrates a method to discover ecological diversity within a virus species using genome-based phylogeny and ecotype simulation, showing heterogeneity in host associations among West Nile Virus ecotypes.

bioRxiv · Dec 12, 2019 · PreprintMicrobiology