D. Lacoste

The trade-off between growth and risk in Kelly's gambling and beyond

The paper generalizes Kelly's gambling model to non-diagonal odds matrices, deriving a risk-growth trade-off and linking it to a game-theoretic formulation.

Pareto-optimal trade-off for phenotypic switching of populations in a stochastic environment

The paper analyzes the trade-off between growth rate and risk in a population's phenotypic switching strategy under stochastic environments, finding similar optimal trade-off curves to Kelly's gambling model.

Universal constraints on selection strength in lineage trees

The paper derives general inequalities that constrain selection strength in lineage trees using theoretical and experimental approaches.

Fluctuation relations and fitness landscapes of growing cell populations

The paper derives fluctuation relations and analyzes fitness landscapes in growing cell populations using forward and backward lineage samplings.

Survival of self-replicating molecules under transient compartmentalization with natural selection

The paper shows that transient compartmentalization enables survival of self-replicating molecules and allows sustained concentration oscillations in a system with a replicase and parasite molecule.

Linking lineage and population observables in biological branching processes

The paper derives fluctuation theorems linking lineage and population-level observables in branching processes and shows how they relate doubling time to generation time.

Transient compartmentalization dynamics in the presence of mutations and noise

The paper extends a framework for transient compartmentalization with selection dynamics by incorporating mutations and noise, showing that noise has minimal impact on phase diagrams due to replication-limited dynamics.

Selection dynamics in transient compartmentalization

The paper demonstrates that selection dynamics in transient compartments can maintain functional replicators by varying parasite amplification and compartment size, with implications for virus-host ecology.