Author

D. N. Sheppard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

D. P. Tieleman· 1 shared P. Vergani· 1 shared S. Prins· 1 shared V. Corradi· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

D. P. Tieleman

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1 paper

Recent·Most cited

Can two wrongs make a right? F508del-CFTR ion channel rescue by second-site mutations in its transmembrane domains

S. Prins, V. Corradi, D. N. Sheppard, D. P. Tieleman, P. Vergani

This study identifies second-site mutations that rescue F508del-CFTR dysfunction by restoring hydrophobic interactions and conformational flexibility at the ICL4/NBD1 interface.

bioRxiv · Sep 7, 2021Biophysics