Author

D. O. Holland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:whole-exome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

H. Tan· 1 shared K. Fedkenheuer· 1 shared L. L. Elnitski· 1 shared M. E. Johnson· 1 shared N. E. Seidel· 1 shared S. Bang-Christensen· 1 shared S. K. Jaiswal· 1 shared V. Gotea· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

H. Tan

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Author profile →

2 papers

Recent·Most cited

SoMAS: Finding somatic mutations associated with alternative splicing in human cancers

H. Tan, V. Gotea, N. E. Seidel, D. O. Holland, K. Fedkenheuer, S. K. Jaiswal, S. Bang-Christensen, L. L. Elnitski

SoMAS identifies somatic mutations linked to alternative splicing in 33 cancer types, revealing 908 genes associated with altered isoform expression across multiple cancers.

bioRxiv · Jul 6, 2023 · PreprintCancer Biology

Stoichiometric balance of protein copy numbers is measurable and functionally significant in a protein-protein interaction network for yeast endocytosis

D. O. Holland, M. E. Johnson

The paper shows that protein copy numbers in yeast endocytosis networks are balanced relative to their binding partners, and this balance affects functional outcomes like complex formation.

bioRxiv · Oct 18, 2017Biophysics