D. Ortega-Del Vecchyo

Demographic Modeling of Admixed Latin American Populations from Whole Genomes

This study infers demographic models of admixed Latin American populations using whole genome data to better capture their complex evolutionary history and genetic diversity patterns.

The Utility of Ancestral and Derived Allele Sharing for Genome-Wide Inferences of Introgression

This study introduces new methods for detecting introgression by incorporating ancestral allele sharing, finding they perform comparably to existing derived allele sharing methods.

Leveraging shared ancestral variation to detect local introgression

The paper introduces a new statistic, D+, to detect local introgression by incorporating both shared ancestral and derived alleles, showing improved precision over existing methods.

A community-maintained standard library of population genetic models

The paper introduces stdpopsim, a community-maintained library for population genetic models, to standardize simulations and facilitate benchmarking of inference tools.

Haplotype-based inference of the distribution of fitness effects

The paper develops a likelihood-based method to infer selection intensity on low-frequency variants using haplotype data and applies it to the UK10K dataset, finding similar proportions of neutral and deleterious variants as previous estimates.

Fst between archaic and present-day samples

This paper develops an analytic theory for FST between archaic and present-day samples, showing how it depends on spatial and temporal separation, and applies it to human populations.