FUCCI tracking shows that Neurog3 levels vary with cell-cycle phase in endocrine-biased pancreatic progenitors
M. E. Bechard, E. D. Bankaitis, A. Ustione, D. Piston, M. A. Magnuson, C. V. E. Wright
The paper shows Neurog3 protein levels vary with cell-cycle phase in pancreatic progenitors, supporting a model where Neurog3 levels coordinate with cell-cycle progression to maintain endocrine-lineage primed status.
bioRxiv · Jun 21, 2017Cell Biology