Author

D. R. Usmanova

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Evolutionary Biology· 2

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

D. Vitkup· 2 shared G. Plata· 2 shared H. H. Wang· 1 shared J. Park· 1 shared M. Konate· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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2 shared papersEvolutionary Biology

D. Vitkup

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2 papers

Recent·Most cited

Ability of the misfolding avoidance hypothesis to explain protein evolutionary rates in the light of empirical evidence

D. R. Usmanova, G. Plata, D. Vitkup

This study evaluates the misfolding avoidance hypothesis by analyzing protein stability and aggregation data in E. coli and H. sapiens, finding no strong correlation between evolutionary rates and protein stability.

bioRxiv · Oct 26, 2020Evolutionary Biology

Molecular function limits divergent protein evolution on planetary timescales

M. Konate, G. Plata, J. Park, D. R. Usmanova, H. H. Wang, D. Vitkup

The paper examines how molecular function constrains protein divergence over time, finding that sequence and structural similarities stabilize after ~1-2 billion years of evolution.

bioRxiv · Jun 14, 2019Evolutionary Biology