Predicting enzyme substrate chemical structure with protein language models
A. Jinich, S. Z. Nazia, A. V. Tellez, D. Rappoport, M. AlQuraishi, K. Y. Rhee
This paper predicts chemical substrate structures for orphan enzymes using protein language models, achieving high accuracy for Mycobacterium tuberculosis SDRs and SAM-methyltransferases.
bioRxiv · Sep 28, 2022 · PreprintMicrobiology