An integrated approach to study chromatin and transcriptional dynamics throughout the cell cycle without pharmacological inhibition
D. Shlyueva, S. Teed-Singer, Y. Zhan, R. Koche, K. Helin
The paper compares chromatin and transcriptional dynamics across cell cycle phases in mESCs using different synchronization methods, finding that CDK1 inhibitor synchronization best mimics G2/M phase.
bioRxiv · Jun 18, 2022 · PreprintCell Biology