Author

D. W. Hogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:software / tool· 1

Frequent Co-Authors

H. van den Bedem· 2 shared J. S. Fraser· 2 shared S. A. Wankowicz· 2 shared A. Raju· 1 shared A. Ravikumar· 1 shared B. Riley· 1 shared D. A. Keedy· 1 shared J. Flowers· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

H. van den Bedem

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2 papers

Recent·Most cited

Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM

S. A. Wankowicz, A. Ravikumar, S. Sharma, B. Riley, A. Raju, D. W. Hogan, J. Flowers, H. van den Bedem, D. A. Keedy, J. S. Fraser

This paper introduces enhanced qFit software for building multiconformer models from structural biology data, improving accuracy and usability.

bioRxiv · Jun 28, 2023Biophysics

Ligand binding remodels protein side chain conformational heterogeneity

S. A. Wankowicz, S. H. P. de Oliveira, D. W. Hogan, H. van den Bedem, J. S. Fraser

The paper measures conformational heterogeneity of protein side chains in ligand-bound and unbound states and finds that ligand binding increases flexibility in distant residues and correlates with inhibitor properties.

bioRxiv · Sep 21, 2021Biophysics