A genomic and structural bioinformatic pipeline identifies candidate type VI secretion antibacterial effector-immunity pairs
A. M. Geller, D. Zlotkin, M. Shalom, N. Blum, A. Levy
The paper develops a genomic and AlphaFold2-based pipeline to identify T6SS effector-immunity pairs, validates four effector proteins and their cognate immunity genes, and explores their mechanisms using bioinformatics and fluorescence microscopy.
bioRxiv · Mar 26, 2023 · PreprintMicrobiology