Systematic dissection of Cas12a-mediated precision genome editing defines design principles for genome-scale variant engineering
Antoine Delhaye, Vlad S Băţăgui, Jana Viktoria Nysten, Daan Troubleyn, Sibylle Chantal Vonesch
The paper systematically analyzes Cas12a genome editing in yeast to identify design principles for efficient and stable variant engineering.
bioRxiv · Jun 29, 2026 · PreprintSynthetic Biology