High-throughput screening for Cushing's disease: therapeutic potential of thiostrepton via cell cycle regulation
Takuro Hakata, Ichiro Yamauchi, Daisuke Kosugi, Taku Sugawa, Haruka Fujita, Kentaro Okamoto, Yohei Ueda, Toshihito Fujii, Daisuke Taura, Nobuya Inagaki
This study identifies thiostrepton as a potential therapy for Cushing's disease by inducing cell cycle arrest in PitNETs through mechanisms independent of FOXM1.
Endocrinology · Jul 18, 2024Peer-reviewedCell Biology