Additive-input encoding fails operator-level target-held-out prediction on current Perturb-seq screens
Kyler J. Fullmer, Dalton Kutzen, Tommy W. Terooatea
The paper shows that additive-input models fail to generalize in Perturb-seq screens when predicting new perturbation targets.
bioRxiv · Oct 8, 2026 · PreprintBioinformatics