Tommy W. Terooatea

This paper introduces scJDO2, a method to separate score and flow operators from single-cell time courses, evaluating their ability to identify unstable cells and bifurcations in hematopoiesis.

The paper shows that additive-input models fail to generalize in Perturb-seq screens when predicting new perturbation targets.

This paper introduces scJDO, a framework for analyzing dynamical sensitivity during cell-state transitions, and applies it to iPSC reprogramming to distinguish productive from diverted fates.

This paper introduces a unified dynamical-systems and control-theoretic model to predict single-cell fate dynamics by integrating pseudotime, RNA velocity, optimal transport, and stochastic trajectories under partial observability.

This study presents a single-cell epigenomic and transcriptomic atlas of aged mice under germ-free conditions, revealing sterile inflammation as an intrinsic ageing feature.