DNA methylation and demethylation underlie the sex difference in estrogen receptor alpha in the arcuate nucleus
Laura R. Cortes, Carla Daniela Cisternas, Iagn N.K.V. Cabahug, Damian Mason, Emma K. Ramlall, Alexandra Castillo‐Ruiz, Nancy Gene Forger
The paper investigates how DNA methylation and demethylation influence sex differences in estrogen receptor alpha (ER) cell numbers in the arcuate nucleus of mice, finding that these epigenetic mechanisms regulate ER expression differently in males and females.
Neuroendocrinology · Sep 21, 2021Peer-reviewedNeuroscience