Toward Rapid Sequenced-Based Detection and Characterization of Causative Agents of Bacteremia
F. Curtis Hewitt, Stephanie L. Guertin, Krista L. Ternus, Kathleen Q. Schulte, Dana R. Kadavy
This paper develops a rapid workflow for detecting and characterizing bacteremia pathogens using metagenomic sequencing and targeted PCR, achieving sensitivities of 1x10^6 and 1x10^5 cells/mL for untargeted and targeted detection, respectively.
bioRxiv · Jul 12, 2017 · PreprintGenomics