Gene Activation and repression by the glucocorticoid receptor are mediated by sequestering Ep300 and two modes of chromatin binding
Avital Sarusi-Portuguez, Ivana Grbeša, Moran Tal, Rachel Deitch, Dana Raz, Ran Weismann, Michal Schwartz, Olga Loza, Myong‐Hee Sung, Tommy Kaplan, Ofir Hakim
This study identifies how the glucocorticoid receptor (GR) activates or represses genes by sequestering Ep300 and interacting with other transcription factors in 3D chromatin structures.
bioRxiv · Sep 10, 2019 · PreprintMolecular Biology