Local optogenetic control of genome editing and tumorigenesis in vivo using wireless implantable optoelectronics
Trisha Bansal, Min‐Kyu Lee, Courtney Coleman, Young-Mee Kim, Yaner Chen, Chad R. Haney, Odile David, Varsha Sreekanth, Raudel O. Avila, Jacob Matsche, Shaluah Vijeth, Dane Hintermueller, Kento Yamagishi, Jiheon Kang, Katie Mowry, , Andrei V. Karginov
This study develops a wireless optogenetic system to control genome editing and tumorigenesis in mice by using light-regulated recombinase and implantable devices.
bioRxiv · Jun 12, 2025 · PreprintBioengineering