An ATF4-centric regulatory network is required for the assembly and function of the OXPHOS system
Umut Cagin, Manuel J. Gómez, Ester Casajús-Pelegay, Rocío Nieto-Arellano, Daniel Arias-Sanroman, Nieves Movilla, Raquel Moreno‐Loshuertos, Maria Esther Gallardo, Fátima Sánchez‐Cabo, José Antonio Enrı́quez
This study identifies ATF4 as a critical regulator of OXPHOS assembly and function by analyzing human and murine cell lines with OXPHOS defects.
bioRxiv · Sep 21, 2023 · PreprintMolecular Biology