Mechanical fracturing of the extracellular matrix patterns the vertebrate heart
Christopher Chan Jin Jie, Daniel Santos-Olivan, Marie‐Christine Ramel, Juliana Sánchez-Posada, Toby G. R. Andrews, Priscilla Paizakis, Emily S. Noël, Alejandro Torres-Sànchez, Rashmi Priya
The paper shows that mechanical fracturing of the cardiac extracellular matrix patterns delamination in the zebrafish heart, independent of biochemical signals.
bioRxiv · Mar 7, 2025 · PreprintDevelopmental Biology