Author

Daniel Sprague

Gritstone Oncology, Inc (United States)Primary ORCID profile (0009-0001-7773-2280 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Daniel SpragueiD5 papers · Duke University

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:large language model· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrienne C. GreeneiD· 1 shared Alexis Mantilla· 1 shared Andrew R. FergusoniD· 1 shared Ankur DhanikiD· 1 shared Bukola Adeoye· 1 shared Calixto Dominguez· 1 shared Christine D. PalmeriD· 1 shared J. Mauro CalabreseiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Adrienne C. GreeneORCID

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2 papers

Recent·Most cited

A novel HLA Class II presentation prediction algorithm deciphers immunogenic CD4 epitopes specific to KRAS G12C

Daniel Sprague, Meghan G. Hart, Joshua S. Klein, Sonia Kounlavouth, Rahulsimham Vegesna, Melissa Rotunno, Lauren D. Kraemer, Rita Zhou, Lindsey Kemp, Adrienne C. Greene, Joshua Araya, Alexis Mantilla, Bukola Adeoye, Calixto Dominguez, Andrew R. Ferguson, , Ankur Dhanik

EDGE-II predicts HLA class II epitopes and identifies immunogenic CD4+ T-cell responses specific to KRAS G12C mutations in cancer.

bioRxiv · Dec 6, 2024 · PreprintBioinformatics

Non-linear sequence similarity between the Xist and Rsx long noncoding RNAs suggests shared functions of tandem repeat domains

Daniel Sprague, Shafagh A. Waters, Jessime M. Kirk, Jeremy Wang, Paul B. Samollow, Paul D. Waters, J. Mauro Calabrese

The paper shows non-linear sequence similarity between Xist and Rsx repeat domains, suggesting shared functional roles through similar protein-binding motif enrichments.

RNA · May 16, 2019Peer-reviewedGenetics