CB1R Regulates Soluble Leptin Receptor Levels via CHOP, Contributing to Hepatic Leptin Resistance
Adi Drori, Asaad Gammal, Shahar Azar, Liad Hinden, Rivka Hadar, Daniel Wesley, Alina Nemirovski, Gergő Szanda, Maayan Salton, Boaz Tirosh, Joseph Tam
This study shows that hepatic CB1R regulates soluble leptin receptor (sOb-R) levels through CHOP, contributing to leptin resistance in diet-induced obesity.
eLife · Nov 19, 2020Peer-reviewedMolecular Biology