Network shape intelligence outperforms AlphaFold2 intelligence in vanilla protein interaction prediction.
Ilyes Abdelhamid, Alessandro Muscoloni, Danny Marc Rotscher, Matthias Lieber, Ulf Markwardt, Carlo Vittorio Cannistraci
This paper introduces Network Shape Intelligence (NSI) and shows it outperforms AlphaFold2 in predicting protein interactions using only local network information without training.
bioRxiv · Aug 10, 2023 · PreprintBioinformatics