Depletion of lamin-associated polypeptide 2alpha leads to chromatin reorganization and binding of A-type lamins to open genomic regions
Daria Filipczak, Fatih Sarigol, Daniel Malzl, Roland Foisner, Nana Naetar
This study shows that LAP2 depletion in fibroblasts causes chromatin reorganization, A-type lamin binding to open regions, and changes in gene expression and chromatin remodeler distribution.
bioRxiv · Aug 7, 2026 · PreprintGenomics