Spontaneous mutations that confer resistance to 2-deoxyglucose act through Hxk2 and Snf1 pathways to regulate gene expression and HXT endocytosis
Samantha R. Soncini, Dakshayini G. Chandrashekarappa, David A. Augustine, Kenny P. Callahan, Allyson F. O’Donnell, Martin C. Schmidt
This study identifies spontaneous mutations in yeast conferring resistance to 2-deoxyglucose, revealing roles for HXK2 and Snf1 pathways in gene expression and hexose transporter endocytosis.
PLoS Genetics · Jul 16, 2020Peer-reviewedGenetics