A targeted computational screen of the SWEETLEAD database reveals FDA-approved compounds with anti-dengue viral activity
Jasmine Moshiri, David A. Constant, Bowen Liu, Roberto Mateo, Steven Kearnes, Paul Novick, Ritika Prasad, Claude Nagamine, Vijay Pande, Karla Kirkegaard
The paper identifies three FDA-approved compounds with anti-dengue activity using computational screening of a safe-in-human database, revealing their potential molecular targets and mechanisms.
mBio · Dec 22, 2020Peer-reviewedMicrobiology