Relationship between branched chain amino acids and type 2 diabetes: a bidirectional Mendelian Randomization study
Jonathan D. Mosley, Mingjian Shi, David Agamasu, Nataraja Sarma Vaitinadin, Venkatesh Locharla Murthy, Ravi V. Shah, Minoo Bagheri, Jane F. Ferguson
This paper uses Mendelian randomization to investigate the causal relationship between branched chain amino acids (BCAAs) and type 2 diabetes, finding that BCAAs are biomarkers of diabetes and higher insulin rather than mediators.
medRxiv · May 23, 2023 · PreprintGenetic & Genomic Medicine