Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs
Rujuta Yashodhan Gadgil, S. Dean Rider, Resha Shrestha, Venicia Alhawach, David C. Hitch, Michael Leffak
The paper shows that microsatellites generate highly mutagenized extrachromosomal circular DNAs through replication-dependent mechanisms and template switching.
NAR Cancer · Apr 8, 2024Peer-reviewedMolecular Biology