Author

David Lähnemann

Düsseldorf University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Johannes KösteriD· 2 shared Alexander SchönhuthiD· 1 shared Alice Carolyn McHardyiD· 1 shared Arndt BorkhardtiD· 1 shared Christopher SchröderiD· 1 shared Elias KutheiD· 1 shared Till HartmanniD· 1 shared Ute FischeriD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBioinformatics

Johannes KösterORCID

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2 papers

Recent·Most cited

Insane in the vembrane: filtering and transforming VCF/BCF files

Till Hartmann, Christopher Schröder, Elias Kuthe, David Lähnemann, Johannes Köster

The paper introduces vembrane, a VCF/BCF filtering tool that consolidates and extends filtering functionality using Python expressions.

Bioinformatics · Dec 14, 2022Peer-reviewedBioinformatics

ProSolo: Accurate Variant Calling from Single Cell DNA Sequencing Data

David Lähnemann, Johannes Köster, Ute Fischer, Arndt Borkhardt, Alice Carolyn McHardy, Alexander Schönhuth

ProSolo improves variant calling accuracy in single-cell DNA sequencing by addressing amplification bias and errors through a probabilistic model and joint modeling with bulk data.

Nature Communications · Nov 18, 2021Peer-reviewedBioinformatics