Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
Gábor Csárdi, Alexander Franks, David S. Choi, Eduardo M. Airoldi, D. Allan Drummond
The paper revisits the relationship between mRNA and protein levels in yeast, finding that mRNA explains over 85% of protein variation when accounting for experimental noise.
bioRxiv · Dec 26, 2014Bioinformatics