Author

Davit Potoyan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter Wolynes· 2 shared Elizabeth Komives· 1 shared Weihua Zheng· 1 shared

Activity by Year

2015-2017 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersSystems Biology

Peter Wolynes

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2 papers

Recent·Most cited

Stochastic dynamics of genetic broadcasting networks

Davit Potoyan, Peter Wolynes

The paper shows that passive thermodynamics in genetic networks can cause a time-scale crisis, which is resolved by actively regulating transcription factor residence times using molecular stripping, illustrated with NF-κB dynamics.

Physical Review E · Nov 3, 2017Peer-reviewedSystems Biology

Molecular stripping in the NFκB/IκB/DNA genetic regulatory network

Davit Potoyan, Weihua Zheng, Elizabeth Komives, Peter Wolynes

The paper investigates the molecular stripping mechanism in the NFκB/IκB/DNA genetic switch using simulations, showing it operates via an allosteric mechanism and conformational selection.

bioRxiv · Oct 2, 2015Biophysics