Low T cell diversity is associated with poor outcome in bladder cancer: a comprehensive longitudinal analysis of the T cell receptor repertoire
Asbjørn Kjær, Nanna Kristjánsdóttir, Randi Istrup Juul, Iver Nordentoft, Karin Birkenkamp‐Demtröder, Johanne Ahrenfeldt, Trine Strandgaard, Deema Radif, Darren Hodgson, Christopher Abbosh, Hugo J.W.L. Aerts, Mads Agerbæk, Jørgen Bjerggaard Jensen, Nicolai J. Birkbak, Lars Dyrskjøt
This study shows that low T cell receptor diversity in bladder cancer patients is linked to poor outcomes and identifies TCR diversity as a potential biomarker for treatment.
Cell Reports Medicine · May 1, 2025Peer-reviewedCancer Biology