Author
Aarhus UniversityORCID 0000-0003-1613-9587Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Christina Espeseth Grand, Laura Iisager, Asbjørn Kjær…·Iben Lyskjær
Asbjørn Kjær, Nanna Kristjánsdóttir, Randi Istrup Juul…·Lars Dyrskjøt
This study shows that low T cell receptor diversity in bladder cancer patients is linked to poor outcomes and identifies TCR diversity as a potential biomarker for treatment.
Mateo Sokač, Asbjørn Kjær, Lars Dyrskjøt…·Nicolai J. Birkbak
GENIUS transforms multi-omics data into images for deep learning analysis to predict metastatic cancer progression from primary tumors.
Johanne Ahrenfeldt, Ditte Sigaard Christensen, Andreas B. Østergaard…·Nicolai J. Birkbak
The paper defines an adaptive-to-innate immune ratio from bulk RNAseq data and shows it correlates with improved prognosis and immunotherapy response, with gender-specific differences.
Saioa López, Emilia L. Lim, Ariana Huebner…·Nicholas McGranahan
The paper investigates how whole genome doubling (WGD) in cancer may mitigate Muller’s Ratchet by reducing negative selection on mutations in essential genes after duplication.
Collin M. Blakely, Thomas B.K. Watkins, Wei Wu…·Trever G. Bivona
The paper investigates genetic epistasis in EGFR-mutant lung cancers using over 2,000 cases, showing that genetic combinations, not single drivers, dominate tumor progression and clinical outcomes.