Dissecting and directing pathology foundation models
Chanwoo Kim, Jakub Kaczmarzyk, Deepika Savant, Zhen Zhao, Peter K. Koo, Su‐In Lee
This paper introduces PICASSO, a framework that makes pathology foundation models interpretable and controllable by decomposing embeddings into human-interpretable visual concepts, enabling new biological insights and downstream applications.
bioRxiv · Jun 16, 2026 · PreprintPathology