Computational saturation mutagenesis of SARS-CoV-1 spike glycoprotein: stability, binding affinity, and comparison with SARS-CoV-2
Adebiyi Sobitan, Vidhyanand Mahase, Raina E. Rhoades, Dejaun Williams, Dongxiao Liu, Yixin Xie, Lin Li, Qiyi Tang, Shaolei Teng
The paper performs computational saturation mutagenesis on SARS-CoV-1 spike protein to assess stability and binding affinity, finding similar mutation effects between SARS-CoV-1 and SARS-CoV-2.
Frontiers in Molecular Biosciences · Dec 9, 2021Peer-reviewedBioinformatics