Qiyi Tang

Hepatitis C Virus Remodels Lipid Droplets to Promote Mitochondrial Fatty Acid Accumulation and Metabolic Activation

This paper investigates how HCV remodels lipid droplets during infection, leading to mitochondrial fatty acid accumulation and metabolic activation, with implications for antiviral strategies.

Computational and Experimental Identification of Potential Neutralizing Peptides Derived from Human ACE2 Against SARS-CoV-2 Infection

This study identifies six ACE2 regions and peptides that can neutralize SARS-CoV-2, showing computational and experimental consistency across variants.

DISC1-PML protein interaction for congenital CMV infection-induced cortical neural progenitor deficit: perturbance of host signaling via viral IE1

This study identifies the role of CMV viral protein IE1 in disrupting host DISC1-PML interaction, leading to neural progenitor deficits in congenital CMV infection.

Genome-wide characterization of SARS-CoV-2 cytopathogenic proteins in the search of antiviral targets

The paper identifies twelve SARS-CoV-2 proteins that induce oxidative stress, inflammation, and cell death, with ORF3a highlighted as a promising antiviral target for drug discovery.

Computational saturation mutagenesis of SARS-CoV-1 spike glycoprotein: stability, binding affinity, and comparison with SARS-CoV-2

The paper performs computational saturation mutagenesis on SARS-CoV-1 spike protein to assess stability and binding affinity, finding similar mutation effects between SARS-CoV-1 and SARS-CoV-2.

Systemic Effects of Missense Mutations on SARS-CoV-2 Spike Glycoprotein Stability and Receptor Binding Affinity

This study quantifies the effects of missense mutations on SARS-CoV-2 spike protein stability and RBD-ACE2 interaction using computational methods.