V3Cell: A Vision-Guided Virtual 3D Cell Framework for Phenotypic Modeling and Perturbation Prediction
Ye Lu, Deng Xun, C Xu, Xiaobo Zhu, Z D Zhang, Pengyu Chen, Xiaomin Yang, Zhengzheng Yan, Jiahua Rao, Hu Huili, J B Hu, Pengwei Hu
V3Cell predicts organoid responses to chemical perturbations using non-invasive bright-field microscopy, creating virtual 3D cell models that mimic real organoids in structure and developmental dynamics.
bioRxiv · Jun 24, 2026 · PreprintBioinformatics